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Medical biophysics 1.



Általános információk

Compulsory subject 1st year 1st semester

Compulsory subject 1st year 1st semester

1.5 hours lecture/week + 2 hours practice/week

Lecture:Monday 14:00-15:10 Szent-Györgyi lecture hall

credit: 3

Tutor: Dr. István Voszka (phone: 459-1500/60234)

If one wants to get exemption from the subject based on the previous studies must give the application to the tutor until Sept. 15. The transcript (original or validated copy) and the detailed topic list of the relevant subjects should be attached. If there is a proper overlap between the topics (at least 75%) we check the knowledge of applicants by a written test containing multiple choice questions at the beginning of the second week of the semester.
The attached sample test shows the style of questions. The real test will contain 40 questions.


Precondition for participationon the laboratory practices, that the student must print the lab report sheet and fill the first page. It is important, that the student should write the questions, that he/she had during preparation for the practice. This will be the basis of discussion .

Rules for lab reports :

1.      Every lab report is considered as a written exam, where three types of grades can be given: „Accepted” „Correction needed” or „Not accepted” .

2.      The basis of acceptability that the teacher must sign the data measured ont he practice and written into part D of the lab report.

3.      After this the evaluation of the data must be done on the attached pages (parts E, F, G). For this application of computer is suggested, but the previously used excel sheets prepared for the given measurement are not allowed to use.

4.      Only the tasks listed in the homepage are required for a certain measurement.

5.      We give help to prepare the lab report by the checklist included in the sheet.

6.      The decision about acceptance of lab report is done usually one week after the measurement. If the grade is “Not accepted”, or “Correction needed” the student is responsible for the correction of mistakes (part H), but the examiner will check it on the exam. During the correction the first version should remain in the lab report in order to see, why the correction was necessary. For correction of small mistakes it is not necessary to include new page.

7.      Doing the missed measurement with another group is possible with previous agreement of both teachers (your own and the teacher of the group, where you want to go).

8.      If you can not do the missed measurement with another group, you have to make the lab report from the data given by the teacher but it is still considered as an absence.

9.      In case if one has more than three “Not accepted” lab reports the signature for the semester is denied.

10. All the lab reports must be shown to the examiner on the semifinal/final exam. If the mistakes are not corrected the result of exam will be one grade worse.

Further conditions for signature:
1.) Participation on at least 75 % of the practices, (in case of more than 3 absences the signature for the semester is denied.) The lab reports must be given to the tutor the week after the measurement.
2. ) The laboratory reports for the measurements should be accepted (in case of more than 3 unaccepted laboratory reports the signature for the semester is denied.)

The form for the lab report can be downloaded here:


The tasks for the acceptance of lab reports are listed here:


The order of laboratory practices can be found here:


In very special cases of more than 3 absences just the head of the Department can make a decision about  the exceptional signature.

Midterm tests:

there will be two midterm tests on the 5th and 9th weeks. It contains 5 questions, from which there are 2 calculations. Retake will be on the 13th and 14th weeks
The first midterm will be from the lecture material of 1-4. weeks and the laboratory practices of the first measurement cycle. The second midterm will be from the lecture material of 5-8. weeks and the laboratory practices of the second measurement cycle. The retake will be from the material of both midterms.
For the signature one must achieve at least 50 points from the 100 possible altogether to be achieved on the two midterms. On the retake 50 points should be achieved from 100.

A sample for the midterm test can be downloaded from here:

Bonus points based on the work during the semester:
If all the lab reports are given to the teacher the week after the measurement in correct form (that means “Accepted”,with maximum one exemption, that is "to be corrected") gets 10 points to the total points of midterms.

Oral exam. First the student takes 2 calculations and a practice question. The first examiner gives a grade for the calculations and one for the practice question after checking the lab reports. If both grades are better, than 1, the student can take 2 theoretical questions, which are asked by the second examiner and will get a grade to both. The final grade is the average of these 4 parts, if all are better, than 1. The grade is rounded up or down according to the decision of the second examiner.

Formula collection can be used on the exams. It can be downloaded here: http://biofiz.semmelweis.hu/upload/file/keplettar_20170908_EN_feltoltheto_1.pdf

if the student on the midterms gets 100 % of the  points for the calculations, and the total number of collected points is at least 80 does not have to take calculation question on the exam and gets 5 for this part.
If the sum of midterm (+ bonus) points is at least 90 (from the possible 110) the student gets a fifth partial grade (which is 5) to the other 4, which increases the average.

If one must go to retake, no favour can be given.
In the second semester only the second semester midterms are counted to the favour. If somebody did not pass the semifinal, cannot get any favour in the second semester.

We call the attention that we do not give permission to take Medical biophysics II. without passing Medical biophysics I.



A tantárgy feladata az orvosképzés céljainak megvalósításában

Our teaching program is evolving continuously. Focused on the general objective of meeting the requirements of the medical curriculum, the courses are also intended to provide specific medical biophysics training.
Todays students will be the physicians of the oncoming decades. In selecting and highlighting topics of study, the first viewpoint is scientific foresight: the knowledge should be conveyed which must be pertinent to ensure first-class professional competence while keeping abreast of the most recent development in the field of study. Our aim is not only the teaching of a specific body of knowledge but also the development of the exact scientific method and concrete problem-solving abilities.

A tantárgy elsajátításához szükséges segédanyagok (könyv, jegyzet, egyéb)

Damjanovich-Fidy-Szöllősi (eds): Medical Biophysics (2009)

Medical biophysics practices (Semmelweis Publisher, 2015)



1 Introduction. Radiations in medicine. Quantities and laws for characterization of common properties of radiations. (Help to understand and learn exam question 1. and to measurements „Light absorption”, „Gamma absorption” and „X-ray”.) II/1. (Miklós Sándor Zoltán Kellermayer) 2017.09.11. pdf  
2 Phenomena related to light and geometrical optics. Fermat principle. Light reflection and refraction on planar and curved surfaces, medical optical devices, geometrical optics of the human eye. (Help to understand and learn exam questions 2. and 3.. and to measurements „Microscopy I.”, „Refractometry” and „Optics of the eye”.) II/2.1.1., II/2.1.2, VIII/2.1. (Miklós Sándor Zoltán Kellermayer) 2017.09.18. pdf  
3 Wave optics as a model. Huygens–Fresnel-principle. the most simple experiment for light interference and its consequences. Resolving power. Light polarization. Color mixing, color vision. (Help to understand and learn exam question 4. and to measurements „Microscopy I. and II.”, „Polarimetry” and „Optics of the eye”.) II/2.1.3. - II/2.1.7. (Levente Herényi) 2017.09.25. pdf  
4 Light as electromagnetic wave and as particle. How these two completely different properties can be proven? (Help to understand and learn exam question 5. and to measurements „Microscopy II.”, “Light emission” and Polarimetry”.) II/2.1.8. (Miklós Sándor Zoltán Kellermayer) 2017.10.02. pdf  
5 Structure of matter, matter wave, atomic and molecular interactions. Atomic force microscopy. (Help to understand and learn exam questions 6. and 7. and to measurement „Resonance”.) (I/1, I/2, X/2) (Tamás Bozó) 2017.10.09. pdf  
6 Many-particle systems. Ideal and real gases. Structure of liquid crystals, thermotropic and lyotropic systems. Help to understand and learn exam questions 8. and 11.(I/3.1, I/3.3.1, I/3.3.5, I/3.4) (Judit Fidy) 2017.10.16. pdf  
7 Boltzmann-distribution and its possible applications. Structure of solids, electric and optical properties of them. (Help to understand and learn exam questions 9.and 10. .) (I/3.2, I/3.3.2, I/3.3.3, I/3.3.4, VII/1.3) (Miklós Sándor Zoltán Kellermayer) 2017.10.30. pdf  
8 Interactions of light with matter. Light scattering, light absorption. Basic principles of absorption spectrometry. (Help to understand and learn exam question 12. and to measurement „Light absorption”.) (II/2.3.1, II/2.3.2, VI/3.1, VI/3.4) (Miklós Sándor Zoltán Kellermayer) 2017.11.06. pdf  
9 Laws of thermal radiation and luminescence. Examples for application of them. Fundamentals of light amplification. Laser oscillator and its conditions. Properties and medical applications of laser radiation. (Help to understand and learn exam questions 13., 14. and 15. and to measurement „Light emission”.) (II/2.2, VI/3.3, VIII/2.2, IX/1) (Miklós Sándor Zoltán Kellermayer) 2017.11.13. pdf   pdf  
10 Atomic nucleus, radioactivity, nuclear radiations. Interactions of nuclear radiations with matter. Radioactive isotopes, physical basis of radioisotope tracing. (Help to understand and learn exam questions 16., 17 .and 18. and to measurements „Nuclear medicine” and “Isotope diagnostics”.) (II/3.2.1, II/3.2.2, II/3.2.3) (László Smeller) 2017.11.20.  
11 Dosimetry, radiation protection. Nuclear measurement techniques.(Help to understand and learn exam questions 19.and 20. and to measurements „Nuclear medicine” and “Dosimetry”.) (II/4.1, II/4.2, II/4.3) (László Smeller) 2017.11.27.  
12 Main problems of nuclear medicine. Radioactive radiations in medical practice. Diagnostic and therapeutic applications of ionizing radiations. Gamma camera.(Help to understand and learn exam question 21. and to measurements „Nuclear medicine” and “Isotope diagnostics”.) (II/3.2.5, VIII/3.2, VIII/4.4) (István Voszka) 2017.12.04.  
13 Signal processing. Classification of signals. Fourier decomposition. Basic electronic circuits. Semiconductor elements in the circuits. Signal conversion and selection, displays. (Help to understand and learn exam question 22, and to measurements “Nuclear medicine”, „Amplifier”, “Pulse generator”, “Skin impedance”, “Coulter counter”, “Audiometry”, “ECG” and “Flow”.) (VII/1.1, VII/1.2.3, VII/1.4, VII/1.5) (András Dezső Kaposi ) 2017.12.11.  



Before starting the test everyone is required to present a Passport or a Residence Permit card.

During the midterm tests and exams one can use:
– non-programmable scientific calculator that cannot store textual information
– blue pen
– ruler and protractor
– pencil
– the Formula Collection provided by the department (NOT your own copy)

No other electric devices (including but not limited to phones, smart watches, tablets) are allowed.

I. midterm test: Oct. 13 (Friday) according to the following:
Szent-Györgyi lecture hall 16:10  groups 1-8
Szent-Györgyi lecture hall 16:45 groups 9-15

Topic List of the First Midterm

II. midterm test: Nov. 7 (Tuesday) according to the following:
Szent-Györgyi lecture hall 19:15  groups 1-8
Szent-Györgyi lecture hall 19:50 groups 9-15

Topic List of the Second Midterm

Biophysics midterm retake (from the material of both midterms) Dec. 5. (Tuesday)19:00 Hevesy lecture hall.
Biophysics midterm second retake (from the material of both midterms) Dec. 12. (Tuesday)19:00 Szent-Györgyi lecture hall. (together with the Hungarian students)



Semifinal exam questions EM 2017-2018 [pdf] 2017.11.21.

Házi feladat példák

Házi feladat példák

week Lectures   Practices
1 9, 10   unit conversion
transposition of formulae
2 20, 21   Microscopy I: 12
further calculations
3     Refractometry: 14
further calculations
4 7, 8, 11    
5 39, 40   Light Emission: 15
6     Microscopy II: 13
7 1–6   Resonance:
8     Problems_Light_Absorption.pdf
9     Problems_Nuclear_Medicine.pdf
10 9, 10, 11, 15   Problems_OpticsOfTheEye.pdf