About me
Miklós Kellermayer is the head of the Theoretical and Translational Medicine Doctoral School and chairman of the Department of Biophysics and Radiation Biology at Semmelweis University, Budapest, Hungary. He obtained his M.D. and Ph.D. degrees from the University of Pécs, Hungary in 1988 and 1998, respectively. He received his D.Sc. degree in 2007 from the Hungarian Academy of Sciences. He became full professor in 2008 at Semmelweis University. He has had several years of international research experience in the fields of muscle physiology and single-molecule biophysics at the University of Washington in Seattle, Washington State University in Pullman and the University of California in Berkeley. He currently focuses on biomolecular mechanics, cytoskeletal and viral nanobiology, protein folding and in vivo imaging. He supervises the Georg von Békésy Biophysics Research Center at Semmelweis University that houses state-of-the-art instrumentation that allows imaging and manipulation from single molecules to small-animal organisms. He served as vice rector of Semmelweis Universsity (2009-2012), and vice dean (2013-2015) and dean (2019-2024) of the Faculty of Medicine. He is a Howard Hughes Medical School International Alumnus, member of the Academia Europaea, president of the Hungarian Biophysical Society and has authored more than 140 original research papers that received citations exceeding 6500; his H-index is 39 (Google Scholar).
Sources
-
TMPyP binding evokes a complex, tunable nanomechanical response in DNANucleic Acids Res. 2024 Aug 12;52(14):8399-8418.
-
Truncated titin is structurally integrated into the human dilated cardiomyopathic sarcomereJ Clin Invest. 2024 Jan 16;134(2):e169753
-
A kétkedés segít, hogy válaszokat találjunkMagyar Kurír 2024. augusztus 30
-
Topography, Spike Dynamics, and Nanomechanics of Individual Native SARS-CoV-2 VirionsNano Lett. 2021 Mar 24;21(6):2675-2680
-
Topology of interaction between titin and myosin thick filaments.J Struct Biol. 2018 Jul;203(1):46-53.
-
Forced phage uncorking: viral DNA ejection triggered by a mechanically sensitive switchNanoscale. 2018 Jan 25;10(4):1898-1904.
-
Optical Trapping Nanometry of Hypermethylated CPG-Island DNA.Biophys J. 2017 Feb 7;112(3):512-522.
-
Force generation by titin folding.Protein Sci. 2017 Jul;26(7):1380-1390.
-
Stepwise reversible nanomechanical buckling in a viral capsid.Nanoscale. 2017 Jan 19;9(3):1136-1143.
-
Extreme resilience in cochleate nanoparticles.Langmuir. 2015 Jan 20;31(2):839-45.
-
Stretching desmin filaments with receding meniscus reveals large axial tensile strengthJ Struct Biol. 2014 Jun;186(3):472-80.
-
Low-force transitions in single titin molecules reflect a memory of contractile historyJ Cell Sci. 2014 Feb 15;127(Pt 4):858-70
-
Structure and assembly-disassembly properties of wild-type transthyretin amyloid protofibrils observed with atomic force microscopyJ Mol Recognit. 2011 May-Jun;24(3):467-76
-
Stepwise dynamics of epitaxially growing single amyloid fibrils.Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):141-4.
-
Reversible mechanical unzipping of amyloid beta-fibrils.J Biol Chem. 2005 Mar 4;280(9):8464-70.
-
Differential actin binding along the PEVK domain of skeletal muscle titin.J Cell Sci. 2004 Nov 15;117(Pt 24):5781-9.
-
Global configuration of single titin molecules observed through chain-associated rhodamine dimersProc Natl Acad Sci U S A. 2001 Dec 4;98(25):14362-7.
-
Folding-unfolding transitions in single titin molecules characterized with laser tweezersScience. 1997 May 16;276(5315):1112-6.